| Player | Team | Opponent | Min | Competition | Date |
|---|---|---|---|---|---|
| Franck Kessié | Atalanta | vs Napoli | 67' | Serie A | 25 Feb 2017 |
| Lorenzo Pellegrini | Sassuolo | vs Cagliari | 34' | Serie A | 22 Dec 2016 |
| Victor Mareco | Brescia | vs Juventus | 71' | Serie A | 20 Mar 2011 |
| Alessandro Diamanti | Brescia | vs Lazio | 74' | Serie A | 3 Oct 2010 |
| Nicolás Burdisso | AS Roma | vs Cagliari | 22' | Serie A | 11 Sept 2010 |