| Player | Team | Opponent | Min | Competition | Date |
|---|---|---|---|---|---|
| Harrison Afful | Columbus Crew | vs FC Cincinnati | 42' | MLS | 9 Jul 2021 |
| Nicolás Acevedo | New York City FC | vs LAFC | 86' | MLS | 29 May 2021 |
| Thierry Henry | Red Bull New York | vs Sporting Kansas City | 27' | MLS | 15 Oct 2011 |
| Nat Borchers | Real Salt Lake | vs Chivas USA | 24' | MLS | 28 Aug 2011 |
| Colin Clark | Houston Dynamo FC | vs Sporting Kansas City | 50' | MLS | 17 Jul 2011 |
| Colin Clark | Houston Dynamo FC | vs Sporting Kansas City | 69' | MLS | 17 Jul 2011 |
| Brian Ching | Houston Dynamo FC | vs Sporting Kansas City | 69' | MLS | 17 Jul 2011 |
| Milos Stojcev | Sporting Kansas City | vs FC Dallas | 57' | MLS | 12 Jun 2011 |
| Javier Morales | Real Salt Lake | vs FC Dallas | 68' | MLS | 30 Oct 2010 |
| Miguel Montaño | Seattle Sounders FC | vs FC Dallas | 56' | MLS | 12 Jul 2010 |
| Pablo Mastroeni | Colorado Rapids | vs Columbus Crew | 77' | MLS | 6 Jun 2010 |