| Player | Team | Opponent | Min | Competition | Date |
|---|---|---|---|---|---|
| Daniel Silva | FC Midtjylland | vs Real Sociedad | 69' | UEFA Europa League | 20 Feb 2025 |
| Alberto Moreno | Villarreal | vs Marseille | 62' | UEFA Europa League | 7 Mar 2024 |
| Manuel Gulde | SC Freiburg | vs Juventus | 44' | UEFA Europa League | 16 Mar 2023 |
| Angeliño | RB Leipzig | vs Manchester City | 79' | UEFA Champions League | 15 Sept 2021 |