| Player | Team | Opponent | Min | Competition | Date |
|---|---|---|---|---|---|
| Julio Cascante | Austin FC | vs Real Salt Lake | 49' | MLS | 15 Aug 2021 |
| Rudy Camacho | CF Montréal | vs Atlanta United FC | 73' | MLS | 4 Aug 2021 |
| Victor Wanyama | CF Montréal | vs Atlanta United FC | 82' | MLS | 4 Aug 2021 |
| Josef Martínez | Atlanta United FC | vs CF Montréal | 82' | MLS | 4 Aug 2021 |
| Darren Mattocks | Vancouver Whitecaps | vs Portland Timbers | 84' | MLS | 26 Aug 2012 |
| Cole Grossman | Columbus Crew | vs Sporting Kansas City | 90' | MLS | 29 Jul 2012 |
| Daniel Cruz | FC Dallas | vs Seattle Sounders FC | 55' | MLS | 21 Aug 2011 |
| Bobby Burling | San Jose Earthquakes | vs Real Salt Lake | 60' | MLS | 24 Jul 2011 |
| Josip Mikulic | Chicago Fire FC | vs LA Galaxy | 90' | MLS | 10 Jul 2011 |
| Tony Tchani | Toronto FC | vs Columbus Crew | 42' | MLS | 23 Apr 2011 |